DENARASE®
The GMP endonuclease from Serratia marcescens for enzymatic DNA removal in bioprocessing.

DENARASE®

- Enzymatic DNA Removal in bioprocessing
- High activity to broad variety of DNA/RNA substrates
- Manufacturing free of animal derived materials and antibiotics
- Endotoxin-free expression host
- High activity and high purity ≥99 %
- Produced under GMP conditions
- Comprehensive technical support by our team of experts
DENARASE® ELISA Kit

- Quantitative analysis of residual Serratia marcescens endonucleases
- Use of a monoclonal antibody enables unmatched accuracy & reproducibility
- Time saving
- Lowest detection (4 pg/mL) and quantification limit (12 pg/mL)
- Broad working range (~32 pg/mL - 1000 pg/mL at OD450)
- Comprehensive technical support by our team of experts
Order DENARASE® and DENARASE® ELISA Kit now!
- DENARASE® R&D-grade
Products for use in research and development
For process development of biologicals such as viral vectors and vaccines. The enzyme cleaves all forms of DNA and RNA and enables a simpler, more efficient downstream process.Purity: ≥ 99%
Activity: > 250 U/µl
Formulation: buffered aqueous glycerol solution
Storage Temperature: -20°C
Estimated Delivery time: 1-2 weeks (depending on region)- Produced in conformity with ISO 9001 standard
- Manufacturing free of animal derived raw materials and antibiotics
- Depending on your application 10 – 60 U/ml is needed
- Net price excluding VAT and shipment costs
- DENARASE® GMP-grade
GMP products for biopharmaceutical manufacturing
For GMP manufacturing of biologicals such as viral vectors and vaccines. The enzyme reduces all forms of DNA and RNA and enables a simpler, more efficient downstream process.Purity: ≥ 99%
Activity: > 250 U/µl
Formulation: buffered aqueous glycerol solution
Storage Temperature: -20°C
Estimated Delivery time: 1-2 weeks (depending on region)- Produced under EU GMP conditions
- Manufacturing free of animal derived raw materials and antibiotics
- Dedicated regulatory support for US-market approvals of pharmaceutical products via own US FDA Drug Master File
- Net price excluding VAT and shipment costs
- DENARASE® ELISA Kit
ELISA Kit for DENARASE® and Benzonase*
For the quantitative analysis of residual serratia marcescens endonucleases in process samples.
Save 20% on your first order with code ELISAKit_20
- The kit consists of a pre-coated micro test plate and all ready to use reagents.
- The capacity of 1 kit is 480 measurements
- Estimated Delivery time: 1-2 weeks (depending on region)
- Net price excluding VAT and shipment costs
*Benzonase Nuclease is a registered trademark of Merck KGaA
- Free Sample
Products for use in research and development
Activity: > 250 U/µl
Formulation: buffered aqueous glycerol solution
Storage Temperature: -20°C
Estimated Delivery time: 1-2 weeks (depending on region)
- Produced in conformity with ISO 9001 standard
- Manufacturing free of animal derived raw materials and antibiotics
- Depending on your application 10 – 60 U/ml is needed
- Net price excluding VAT and shipment costs

GMP products for biopharmaceutical manufacturing
Activity: > 250 U/µl
Formulation: buffered aqueous glycerol solution
Storage Temperature: -20°C
Estimated Delivery time: 1-2 weeks (depending on region)
- Produced under EU GMP conditions
- Manufacturing free of animal derived raw materials and antibiotics
- Dedicated regulatory support for US-market approvals of pharmaceutical products via own US FDA Drug Master File
- Net price excluding VAT and shipment costs

ELISA Kit for DENARASE® and Benzonase*
For the quantitative analysis of residual serratia marcescens endonucleases in process samples.
Save 20% on your first order with code ELISAKit_20
- The kit consists of a pre-coated micro test plate and all ready to use reagents.
- The capacity of 1 kit is 480 measurements
- Estimated Delivery time: 1-2 weeks (depending on region)
- Net price excluding VAT and shipment costs
*Benzonase Nuclease is a registered trademark of Merck KGaA

Are you looking for the latest news about DENARASE®?
Do you want to reduce costs in your viral vector manufacturing process? Bring in DENARASE®!
Endonucleases are widely used in the manufacturing of viral vectors for cell and gene therapies. BioPhorum recently highlighted an industry challenge: How to compare the technical performance of Serratia marcescens endonucleases such as Benzonase® and DENARASE®?
We generated a set of comparison data to facilitate the comparison of process-relevant parameters such as enzyme activities and concentration.
Get in touch with our DENARASE® expert team!

Vaishnavi Devarakonda
DENARASE® Sales

Melissa Rangel
DENARASE® Sales
Need support? Contact me!

Cynthia Hofmann-Orsetti
DENARASE® Sales
Need support? Contact me!